In the normal course of events, it takes a week (or two or three) for the bugs in each month’s Windows and Office security patches to shake out. This month’s patches are no exception. There are lots of reports of problems with IE and Edge, for example, and many more are piling up.
In the normal course of events, the fresh-off-the-press security patches present more of a threat to most people, in the short term, than do the problems the patches are supposed to fix. You have to patch sooner or later, but by waiting for the screams of pain to die down, you can save yourself some major headaches.